Co-vaccination study for COVID-19 vaccinated people

The aim of the CoCoVaccine study was to better understand the short-, medium- and long-term serological immune response in SARS-CoV-2 vaccinated individuals. To this end, over 6,000 participants were included in the study, mainly healthcare professionals who had each received at least one vaccination against COVID-19.
The research interest lay in the following questions: Do you know your SARS-CoV-2 antibody status? With which antibody constellations do COVID-19 infections and illnesses occur? From what titer are you protected? Are asymptomatic infections possible after vaccination, which can be passed on to people in the vicinity despite (or precisely because of) the lack of signs of illness? What does the presumed correlation between antibody titres and disease risk or disease severity shown in the diagram actually look like?
Contact for participants
Please note that the telephone study hotline for the KoCo vaccination study is no longer active.
You can still reach us by e-mail:
KoCo19@med.uni-muenchen.de
About the study and information for participants
Study results
Understanding the Omicron Variant Impact in Healthcare Workers: Insights from the Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf) on Risk Factors for Breakthrough and Reinfections.
Janke C, Rubio-Acero R, Weigert M, Reinkemeyer C, Khazaei Y, Kleinlein L, Le Gleut R, Radon K, Hannes M, Picasso F, et al.
Viruses. 2024; 16(10):1556.
The Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf): Risk Factors and Determinants of Immune Response in Healthcare Workers.
Reinkemeyer C, Khazaei Y, Weigert M, Hannes M, Le Gleut R, Plank M, Winter S, Noreña I, Meier T, Xu L, et al.
Viruses. 2023; 15(7):1574.
Study cooperations
- ORCHESTRA Cohort (Connecting European Cohorts to increase common and effective SARS-CoV-2 Response)
- RisCoin (risk factors for Covid-19 vaccination failure) study, LMU Klinikum
- CoVaKo: Corona vaccine consortium
- Bavarian outpatient Covid-19 monitor (BaCoM)
KoCoImpf study team


The project was also funded by the pan-European consortium ORCHESTRA. The ORCHESTRA project has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 101016167. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.