Publikationen bis 2005

How robust are laboratory measures of growth hormone status?

Strasburger CJ, Bidlingmaier M.

Horm Res. 2005;64 Suppl 2:1-5.


Systemic regulation of angiogenesis and matrix degradation in bone regeneration--distraction osteogenesis compared to rigid fracture healing

Weiss S, Zimmermann G, Baumgart R, Kasten P, Bidlingmaier M, Henle P.

Bone. 2005 Dec;37(6):781-90. Epub 2005 Oct 3.


Postoperative evaluation of patients with acromegaly: clinical significance and timing of oral glucose tolerance testing and measurement of (free) insulin-like growth factor I, acid-labile subunit, and growth hormone-binding protein levels

Feelders RA, Bidlingmaier M, Strasburger CJ, Janssen JA, Uitterlinden P, Hofland LJ, Lamberts SW, van der Lely AJ, de Herder WW.

J Clin Endocrinol Metab. 2005 Dec;90(12):6480-9. Epub 2005 Sep 13


Four-year follow-up of acromegalic patients treated with the new long-acting formulation of Lanreotide (Lanreotide Autogel)

Gutt B, Bidlingmaier M, Kretschmar K, Dieterle C, Steffin B, Schopohl J.

Exp Clin Endocrinol Diabetes. 2005 Mar;113(3):139-44.


Short stature caused by a biologically inactive mutant growth hormone (GH-C53S)

Besson A, Salemi S, Deladoëy J, Vuissoz JM, Eblé A, Bidlingmaier M, Bürgi S, Honegger U, Flück C, Mullis PE.

J Clin Endocrinol Metab. 2005 May;90(5):2493-9. Epub 2005 Feb 15.


Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats

Tang-Christensen M, Vrang N, Ortmann S, Bidlingmaier M, Horvath TL, Tschöp M.

Endocrinology. 2004 Oct;145(10):4645-52. Epub 2004 Jul 1.


Growth hormone (GH) insensitivity syndrome due to a GH receptor truncated after Box1, resulting in isolated failure of STAT 5 signal transduction

Milward A, Metherell L, Maamra M, Barahona MJ, Wilkinson IR, Camacho-Hübner C, Savage MO, Bidlingmaier M, Clark AJ, Ross RJ, Webb SM.

J Clin Endocrinol Metab. 2004 Mar;89(3):1259-66. Erratum in: J Clin Endocrinol Metab. 2009 Jul;94(7):2674. Bidlingmaier, C M [corrected to Bidlingmaier, M].


Problems with GH doping in sports

Bidlingmaier M, Wu Z, Strasburger CJ.

J Endocrinol Invest. 2003 Sep;26(9):924-31.


Reboxetine acutely stimulates cortisol, ACTH, growth hormone and prolactin secretion in healthy male subjects

Schüle C, Baghai T, Schmidbauer S, Bidlingmaier M, Strasburger CJ, Laakmann G.

Psychoneuroendocrinology. 2004 Feb;29(2):185-200.


Decreasing resistance in the maternal uterine and peripheral arterial system is apparently unrelated to plasma and urinary levels of nitrite/nitrate and cyclic-guanosinmonophosohate during the course of normal pregnancies

Schiessl B, Strasburger CJ, Bidlingmaier M, Spannagl M, Ugele B, Kainer F.

J Perinat Med. 2003;31(4):281-6.


Serum leptin monitoring in anorectic patients during refeeding therapy

Lob S, Pickel J, Bidlingmaier M, Schaaf L, Backmund H, Gerlinghoff M, Stalla GK.

Exp Clin Endocrinol Diabetes. 2003 Aug;111(5):278-82.


The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, Friedman JM, Liu H, Pinto S, Colmers WF, Cone RD, Horvath TL.

Neuron. 2003 Feb 20;37(4):649-61.


A new nonisotopic, highly sensitive assay for the measurement of human placental growth hormone: development and clinical implications

Wu Z, Bidlingmaier M, Friess SC, Kirk SE, Buchinger P, Schiessl B, Strasburger CJ.

J Clin Endocrinol Metab. 2003 Feb;88(2):804-11.


Endocrinological effects of mirtazapine in healthy volunteers

Schüle C, Baghai T, Bidlingmaier M, Strasburger C, Laakmann G.

Prog Neuropsychopharmacol Biol Psychiatry. 2002 Dec;26(7-8):1253-61.


Impact of experimental blockade of peripheral growth hormone (GH) receptors on the kinetics of endogenous and exogenous GH removal in healthy women and men

Veldhuis JD, Bidlingmaier M, Anderson SM, Evans WS, Wu Z, Strasburger CJ.

J Clin Endocrinol Metab. 2002 Dec;87(12):5737-45.


The influence of mirtazapine on anterior pituitary hormone secretion in healthy male subjects

Schüle C, Baghai T, Goy J, Bidlingmaier M, Strasburger C, Laakmann G.

Psychopharmacology (Berl). 2002 Aug;163(1):95-101. Epub 2002 Jun 27.


Systemic regulation of distraction osteogenesis: a cascade of biochemical factors

Weiss S, Baumgart R, Jochum M, Strasburger CJ, Bidlingmaier M.

J Bone Miner Res. 2002 Jul;17(7):1280-9.


Quantification of the soluble leptin receptor in human blood by ligand-mediated immunofunctional assay

Wu Z, Bidlingmaier M, Liu C, De Souza EB, Tschöp M, Morrison KM, Strasburger CJ.

J Clin Endocrinol Metab. 2002 Jun;87(6):2931-9.


The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression

Hofmann S, Grasberger H, Jung P, Bidlingmaier M, Vlotides J, Janssen OE, Landgraf R.

Eur J Med Res. 2002 Apr 30;7(4):171-6.


Differential regulation of insulin-like growth factor-(IGF) I and IGF-binding protein (IGFBP) secretion by human peripheral blood mononuclear cells

Auernhammer CJ, Fottner C, Engelhardt D, Bidlingmaier M, Strasburger CJ, Weber MM.

Horm Res. 2002;57(1-2):15-21.


Ghrelin drives GH secretion during fasting in man

Muller AF, Lamberts SW, Janssen JA, Hofland LJ, Koetsveld PV, Bidlingmaier M, Strasburger CJ, Ghigo E, Van der Lely AJ.

Eur J Endocrinol. 2002 Feb;146(2):203-7.


Evaluation of a salivary based combined dexamethasone/CRH test in patients with major depression

Baghai TC, Schüle C, Zwanzger P, Minov C, Holme C, Padberg F, Bidlingmaier M, Strasburger CJ, Rupprecht R.

Psychoneuroendocrinology. 2002 Apr;27(3):385-99.


Normal values of insulin-like growth factor I and their clinical utility in adults

Strasburger CJ, Bidlingmaier M, Wu Z, Morrison KM.

Horm Res. 2001;55 Suppl 2:100-5. Review.


Effects of fasting and pegvisomant on the GH-releasing hormone and GH-releasing peptide-6 stimulated growth hormone secretion

Muller AF, Janssen JA, Lamberts SW, Bidlingmaier M, Strasburger CJ, Hofland L, van der Lely AJ.

Clin Endocrinol (Oxf). 2001 Oct;55(4):461-7.


Doping with growth hormone

Bidlingmaier M, Wu Z, Strasburger CJ.

J Pediatr Endocrinol Metab. 2001 Sep-Oct;14(8):1077-83. Review.


High-dose leptin activates human leukocytes via receptor expression on monocytes

Zarkesh-Esfahani H, Pockley G, Metcalfe RA, Bidlingmaier M, Wu Z, Ajami A, Weetman AP, Strasburger CJ, Ross RJ.

J Immunol. 2001 Oct 15;167(8):4593-9.


Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors

Maamra M, Bidlingmaier M, Postel-Vinay MC, Wu Z, Strasburger CJ, Ross RJ.

Endocrinology. 2001 Oct;142(10):4389-93.


Findings and theoretical considerations on the usefulness of the acid-labile subunit in the monitoring of acromegaly

Morrison KM, Wu Z, Bidlingmaier M, Strasburger CJ.

Growth Horm IGF Res. 2001 Jun;11 Suppl A:S61-3. Review.


Lowering total plasma insulin-like growth factor I concentrations by way of a novel, potent, and selective growth hormone (GH) receptor antagonist, pegvisomant (B2036-peg), augments the amplitude of GH secretory bursts and elevates basal/nonpulsatile GH release in healthy women and men

Veldhuis JD, Bidlingmaier M, Anderson SM, Wu Z, Strasburger CJ.

J Clin Endocrinol Metab. 2001 Jul;86(7):3304-10.


Post-prandial decrease of circulating human ghrelin levels

Tschöp M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R, Folwaczny C.

J Endocrinol Invest. 2001 Jun;24(6):RC19-21.


Changes in non-22-kilodalton (kDa) isoforms of growth hormone (GH) after administration of 22-kDa recombinant human GH in trained adult males

Wallace JD, Cuneo RC, Bidlingmaier M, Lundberg PA, Carlsson L, Boguszewski CL, Hay J, Boroujerdi M, Cittadini A, Dall R, Rosén T, Strasburger CJ.

J Clin Endocrinol Metab. 2001 Apr;86(4):1731-7.


Immunoassay measurements of leptin

Bidlingmaier M, Tschoep M.

Methods Mol Biol. 2001;155:323-30. Review. No abstract available.


The response of molecular isoforms of growth hormone to acute exercise in trained adult males

Wallace JD, Cuneo RC, Bidlingmaier M, Lundberg PA, Carlsson L, Boguszewski CL, Hay J, Healy ML, Napoli R, Dall R, Rosén T, Strasburger CJ.

J Clin Endocrinol Metab. 2001 Jan;86(1):200-6.


Blockade of the growth hormone (GH) receptor unmasks rapid GH-releasing peptide-6-mediated tissue-specific insulin resistance

Muller AF, Janssen JA, Hofland LJ, Lamberts SW, Bidlingmaier M, Strasburger CJ, van der Lely AJ.

J Clin Endocrinol Metab. 2001 Feb;86(2):590-3.


Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo

Brunner C, Seiderer J, Schlamp A, Bidlingmaier M, Eigler A, Haimerl W, Lehr HA, Krieg AM, Hartmann G, Endres S.

J Immunol. 2000 Dec 1;165(11):6278-86.


Test method: GH

Bidlingmaier M, Wu Z, Strasburger CJ.

Baillieres Best Pract Res Clin Endocrinol Metab. 2000 Mar;14(1):99-109. Review.


Short-term fasting abolishes the sex-related difference in GH and leptin secretion in humans.

Maccario M, Aimaretti G, Corneli G, Gauna C, Grottoli S, Bidlingmaier M, Strasburger CJ, Dieguez C, Casanueva FF, Ghigo E.

Am J Physiol Endocrinol Metab. 2000 Aug;279(2):E411-6.


Acromegaly caused by secretion of growth hormone by a non-Hodgkin's lymphoma

Beuschlein F, Strasburger CJ, Siegerstetter V, Moradpour D, Lichter P, Bidlingmaier M, Blum HE, Reincke M.

N Engl J Med. 2000 Jun 22;342(25):1871-6. No abstract available.


Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant

Trainer PJ, Drake WM, Katznelson L, Freda PU, Herman-Bonert V, van der Lely AJ, Dimaraki EV, Stewart PM, Friend KE, Vance ML, Besser GM, Scarlett JA, Thorner MO, Parkinson C, Klibanski A, Powell JS, Barkan AL, Sheppard MC, Malsonado M, Rose DR, Clemmons DR, Johannsson G, Bengtsson BA, Stavrou S, Kleinberg DL, Cook DM, Phillips LS, Bidlingmaier M, Strasburger CJ, Hackett S, Zib K, Bennett WF, Davis RJ.

N Engl J Med. 2000 Apr 20;342(16):1171-7.


Mirtazapine: an inhibitor of cortisol secretion that does not influence growth hormone and prolactin secretion

Laakmann G, Schüle C, Baghai T, Waldvogel E, Bidlingmaier M, Strasburger C.

J Clin Psychopharmacol. 2000 Feb;20(1):101-3. No abstract available.


Dehydroepiandrosterone replacement in women with adrenal insufficiency

Arlt W, Callies F, van Vlijmen JC, Koehler I, Reincke M, Bidlingmaier M, Huebler D, Oettel M, Ernst M, Schulte HM, Allolio B.

N Engl J Med. 1999 Sep 30;341(14):1013-20.


Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH

Thorner MO, Strasburger CJ, Wu Z, Straume M, Bidlingmaier M, Pezzoli SS, Zib K, Scarlett JC, Bennett WF.

J Clin Endocrinol Metab. 1999 Jun;84(6):2098-103.


Detection of doping with human growth hormone

Wu Z, Bidlingmaier M, Dall R, Strasburger CJ.

Lancet. 1999 Mar 13;353(9156):895. No abstract available.


Cytokines and therapeutic oligonucleotides

Hartmann G, Bidlingmaier M, Eigler A, Hacker U, Endres S.

Cytokines Cell Mol Ther. 1997 Dec;3(4):247-56. Review.


Spontaneous and cationic lipid-mediated uptake of antisense oligonucleotides in human monocytes and lymphocytes

Hartmann G, Krug A, Bidlingmaier M, Hacker U, Eigler A, Albrecht R, Strasburger CJ, Endres S.

J Pharmacol Exp Ther. 1998 May;285(2):920-8.


Effects of growth hormone and insulin-like growth factor I binding to natural killer cells

Bidlingmaier M, Auernhammer CJ, Feldmeier H, Strasburger CJ.

Acta Paediatr Suppl. 1997 Nov;423:80-1.


Oligonucleotides: extrapolating from in vitro to in vivo

Hartmann G, Bidlingmaier M, Jahrsdörfer B, Endres S.

Nat Med. 1997 Jul;3(7):702. No abstract available.